Essential Oils: Pharmaceutical Applications and Encapsulation Strategies into Lipid-Based Delivery Systems

Essential oils are being studied for more than 60 years, but a growing interest has emerged in the recent decades due to a desire for a rediscovery of natural remedies. Essential oils are known for millennia and, already in prehistoric times, they were used for medicinal and ritual purposes due to t...

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Main Authors: Cinzia Cimino (Author), Oriana Maria Maurel (Author), Teresa Musumeci (Author), Angela Bonaccorso (Author), Filippo Drago (Author), Eliana Maria Barbosa Souto (Author), Rosario Pignatello (Author), Claudia Carbone (Author)
Format: Book
Published: MDPI AG, 2021-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Cinzia Cimino  |e author 
700 1 0 |a Oriana Maria Maurel  |e author 
700 1 0 |a Teresa Musumeci  |e author 
700 1 0 |a Angela Bonaccorso  |e author 
700 1 0 |a Filippo Drago  |e author 
700 1 0 |a Eliana Maria Barbosa Souto  |e author 
700 1 0 |a Rosario Pignatello  |e author 
700 1 0 |a Claudia Carbone  |e author 
245 0 0 |a Essential Oils: Pharmaceutical Applications and Encapsulation Strategies into Lipid-Based Delivery Systems 
260 |b MDPI AG,   |c 2021-03-01T00:00:00Z. 
500 |a 10.3390/pharmaceutics13030327 
500 |a 1999-4923 
520 |a Essential oils are being studied for more than 60 years, but a growing interest has emerged in the recent decades due to a desire for a rediscovery of natural remedies. Essential oils are known for millennia and, already in prehistoric times, they were used for medicinal and ritual purposes due to their therapeutic properties. Using a variety of methods refined over the centuries, essential oils are extracted from plant raw materials: the choice of the extraction method is decisive, since it determines the type, quantity, and stereochemical structure of the essential oil molecules. To these components belong all properties that make essential oils so interesting for pharmaceutical uses; the most investigated ones are antioxidant, anti-inflammatory, antimicrobial, wound-healing, and anxiolytic activities. However, the main limitations to their use are their hydrophobicity, instability, high volatility, and risk of toxicity. A successful strategy to overcome these limitations is the encapsulation within delivery systems, which enable the increase of essential oils bioavailability and improve their chemical stability, while reducing their volatility and toxicity. Among all the suitable platforms, our review focused on the lipid-based ones, in particular micro- and nanoemulsions, liposomes, solid lipid nanoparticles, and nanostructured lipid carriers. 
546 |a EN 
690 |a extraction method 
690 |a anti-inflammatory 
690 |a antioxidant 
690 |a antimicrobial 
690 |a wound healing 
690 |a anxiolytic 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Pharmaceutics, Vol 13, Iss 3, p 327 (2021) 
787 0 |n https://www.mdpi.com/1999-4923/13/3/327 
787 0 |n https://doaj.org/toc/1999-4923 
856 4 1 |u https://doaj.org/article/89a3e879b4094c8c9c0c24d0ac054b6b  |z Connect to this object online.