The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway

• Κύριοι συγγραφείς: Hajer Tlili (Συγγραφέας), Anca Macovei (Συγγραφέας), Daniela Buonocore (Συγγραφέας), Manuela Lanzafame (Συγγραφέας), Hanen Najjaa (Συγγραφέας), Anita Lombardi (Συγγραφέας), Andrea Pagano (Συγγραφέας), Maurizia Dossena (Συγγραφέας), Manuela Verri (Συγγραφέας), Abdelkarim Ben Arfa (Συγγραφέας), Mohamed Neffati (Συγγραφέας), Enrico Doria (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2021-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background Hyperactivation of mechanistic target of rapamycin (mTOR) signaling pathway is involved in the regulation of cellular growth, proliferation, and more in general, is a common phenomenon in most types of cancers. Thus, natural substances targeting this pathway can be of great thera...