Sodium aescinate inhibits microglia activation through NF-κB pathway and exerts neuroprotective effect

• Main Authors: Fei Xu (Author), Yiguo Jiang (Author), Xiaoyu Wang (Author), Li Shen (Author), Yan Yan (Author), Dongkai Guo (Author), Cheng Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Microglia are resident immune cells of the central nervous system that sense environmental changes and maintain central nervous system homeostasis. Dysfunctional microglia produce toxic mediators that lead to neuronal death. Recent studies suggest that Sodium Aescinate has a neuroprotect...