Efficacy of typhoid conjugate vaccine in Nepal: final results of a phase 3, randomised, controlled trial

• Main Authors: Mila Shakya, MPH (Author), Merryn Voysey, DPhil (Author), Katherine Theiss-Nyland, PhD (Author), Rachel Colin-Jones, MA (Author), Dikshya Pant, FCPS (Author), Anup Adhikari, MA (Author), Susan Tonks, BSc (Author), Yama F Mujadidi, MSc (Author), Peter O'Reilly, MBBCh (Author), Olga Mazur, MSc (Author), Sarah Kelly, MSc (Author), Xinxue Liu, PhD (Author), Archana Maharjan, MA (Author), Ashata Dahal, MPH (Author), Naheeda Haque, PharmD (Author), Anisha Pradhan, BSc (Author), Suchita Shrestha, MPH (Author), Manij Joshi, BPharm (Author), Nicola Smith, MBBCh (Author), Jennifer Hill, PhD (Author), Jenny Clarke, PhD (Author), Lisa Stockdale, PhD (Author), Elizabeth Jones, BMedSc (Author), Timothy Lubinda, MSc (Author), Binod Bajracharya, MD (Author), Sabina Dongol, DPhil (Author), Abhilasha Karkey, DPhil (Author), Stephen Baker, ProfPhD (Author), Gordan Dougan, ProfPhD (Author), Virginia E Pitzer, ScD (Author), Kathleen M Neuzil, ProfMD (Author), Shrijana Shrestha, ProfMD (Author), Buddha Basnyat, ProfFRCPE (Author), Andrew J Pollard, ProfFMedSci (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Typhoid fever is a major public health problem in low-resource settings. Vaccination can help curb the disease and might reduce transmission. We have previously reported an interim analysis of the efficacy of typhoid conjugate vaccine (TCV) in Nepali children. Here we report the...