Hepatoprotective effects of silymarin in management of liver injury caused by tuberculosis treatment
Tuberculosis (TB) is a chronic infection of global-health concern because of its high incidence, costly medical treatment, drug resistance and risk of co-infections. Anti-TB treatment involves a combination of drugs with high degree of liver toxicity, leading to drug-induced liver injury in 2-28% of...
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| Format: | Book |
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BioExcel Publishing Ltd,
2023-01-01T00:00:00Z.
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| Summary: | Tuberculosis (TB) is a chronic infection of global-health concern because of its high incidence, costly medical treatment, drug resistance and risk of co-infections. Anti-TB treatment involves a combination of drugs with high degree of liver toxicity, leading to drug-induced liver injury in 2-28% of patients who receive anti-TB treatment. In this case report, a patient with TB experienced drug-induced liver injury, and the initiation of treatment with silymarin 140 mg three-times daily resulted in a significant hepatoprotective effects as shown by the decreased liver enzyme activity. This article is part of the Current clinical use of silymarin in the treatment of toxic liver diseases: a case series Special Issue: https://www.drugsincontext.com/special_issues/ current-clinical-use-of-silymarin-in-the-treatmentof- toxic-liver-diseases-a-case-series |
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| Item Description: | 10.7573/dic.2023-2-11 1740-4398 |