Mobocertinib: Mechanism of action, clinical, and translational science

Abstract Epidermal growth factor receptor (EGFR) exon 20 insertion (ex20ins) mutations represent ~6%-12% of all EGFR‐mutated non‐small cell lung cancer (NSCLC) cases. First‐, second‐, and third‐generation tyrosine kinase inhibitors (TKIs) have limited clinical activity against EGFR ex20ins mutations...

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Main Authors: Michael J. Hanley (Author), D. Ross Camidge (Author), Robert J. Fram (Author), Neeraj Gupta (Author)
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出版: Wiley, 2024-03-01T00:00:00Z.
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