Neonatal hypoxic-ischemic encephalopathy after acute carbon monoxide intoxication during pregnancy. A case report and brief review of the literature

Carbon monoxide (CO) poisoning during pregnancy is a rare occurrence, associated with high maternal and fetal mortality rates. As CO can cross the placenta, leading to intrauterine hypoxia, CO intoxication can result in neurological sequelae and neurologic complications in fetuses who survive. We re...

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Main Authors: Cristina Tuoni (Author), Giulia Nuzzi (Author), Rosa Teresa Scaramuzzo (Author), Simona Fiori (Author), Luca Filippi (Author)
Format: Book
Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Cristina Tuoni  |e author 
700 1 0 |a Giulia Nuzzi  |e author 
700 1 0 |a Giulia Nuzzi  |e author 
700 1 0 |a Rosa Teresa Scaramuzzo  |e author 
700 1 0 |a Simona Fiori  |e author 
700 1 0 |a Simona Fiori  |e author 
700 1 0 |a Luca Filippi  |e author 
245 0 0 |a Neonatal hypoxic-ischemic encephalopathy after acute carbon monoxide intoxication during pregnancy. A case report and brief review of the literature 
260 |b Frontiers Media S.A.,   |c 2023-11-01T00:00:00Z. 
500 |a 2296-2360 
500 |a 10.3389/fped.2023.1264855 
520 |a Carbon monoxide (CO) poisoning during pregnancy is a rare occurrence, associated with high maternal and fetal mortality rates. As CO can cross the placenta, leading to intrauterine hypoxia, CO intoxication can result in neurological sequelae and neurologic complications in fetuses who survive. We report a case of a preterm newborn acutely exposed to CO in-utero and delivered by emergent cesarean section at the 31st week of gestation due to the severe burns suffered by the mother following an indoor boiler explosion. As CO has serious adverse effects both on the mother and fetus, it is important to recognize and treat poisoning in a timely manner. Despite maternal blood CO levels, CO intoxication at critical stage of central nervous system development can lead to hypoxic-ischemic lesions, thus interdisciplinary care and follow up for these patients are mandatory. 
546 |a EN 
690 |a carbon monoxide intoxication 
690 |a hypoxic-ischemic encephalopathy 
690 |a fetal brain damage 
690 |a carboxyhemoglobin 
690 |a cerebral palsy 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pediatrics, Vol 11 (2023) 
787 0 |n https://www.frontiersin.org/articles/10.3389/fped.2023.1264855/full 
787 0 |n https://doaj.org/toc/2296-2360 
856 4 1 |u https://doaj.org/article/8a26b4ad28a6495f85bf3e776ff355e1  |z Connect to this object online.