Targeting the intracellular environment in cystic fibrosis: restoring autophagy as a novel strategy to circumvent the CFTR defect
Cystic fibrosis (CF) patients harboring the most common deletion mutation of the cystic fibrosis transmembrane conductance regulator (CFTR), F508del, are poor responders to potentiators of CFTR channel activity which can be used to treat a small subset of CF patients who genetically carry plasma mem...
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Main Authors: | Valeria Rachela Villella (Author), Speranza eEsposito (Author), Emanuela eBruscia (Author), Maria Chiara eMaiuri (Author), Valeria eRaia (Author), Guido eKroemer (Author), Luigi eMaiuri (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2013-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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