Rapid progression of disease in two cases of undifferentiated endometrial carcinoma

Undifferentiated endometrial carcinoma, a rare histopathologic diagnosis, has a poor prognosis with high risk of progression during or shortly after completion of adjuvant treatment. We present two cases of undifferentiated endometrial carcinoma: one in a postmenopausal female who experienced recurr...

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Bibliographic Details
Main Authors: Krista S. Pfaendler (Author), Leslie M. Randall (Author)
Format: Book
Published: Elsevier, 2019-02-01T00:00:00Z.
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Summary:Undifferentiated endometrial carcinoma, a rare histopathologic diagnosis, has a poor prognosis with high risk of progression during or shortly after completion of adjuvant treatment. We present two cases of undifferentiated endometrial carcinoma: one in a postmenopausal female who experienced recurrent disease immediately after completion of adjuvant treatment and one in a premenopausal female who experienced disease progression while receiving adjuvant treatment. These cases exemplify the aggressive behavior of undifferentiated endometrial carcinoma and suggest the need for a more effective treatment in the upfront setting than the current standard of care for endometrioid endometrial adenocarcinoma. Keywords: Undifferentiated endometrial carcinoma, Endometrial cancer, Dedifferentiated endometrial carcinoma
Item Description:2352-5789
10.1016/j.gore.2019.01.004