Case Report: Anterior Scleritis Presenting as a Primary Ocular Manifestation in Multisystem Inflammatory Syndrome in Children With COVID-19

• Main Authors: Daisuke Matsubara (Author), Daisuke Tamura (Author), Yuka Kasuya (Author), Yoshitaka Mizobe (Author), Mami Hiwada (Author), Mitsuru Seki (Author), Shinji Makino (Author), Takanori Yamagata (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2296-2360; 10.3389/fped.2022.943652
• Keywords: multisystem inflammatory syndrome in children; COVID-19; scleritis; Kawasaki disease; conjunctivitis; fundus findings; Pediatrics; RJ1-570
• Source: Frontiers in Pediatrics, Vol 10 (2022)

Multisystem inflammatory syndrome in children (MIS-C) is a newly defined hyperinflammatory disease linked to antecedent coronavirus disease 2019. Patients with MIS-C present with various symptoms, and ocular findings such as mild bilateral conjunctivitis are relatively common. However, detailed descriptions of severe ocular reports associated with MIS-C are scarce in the current literature. Here we report a case of MIS-C in a Japanese boy, with severe eye manifestations in the form of anterior scleritis as the primary MIS-C symptom. Detailed ocular examinations by ophthalmologists may be key for clarifying the pathophysiology of MIS-C.