Effect of particle size on the oral absorption of isoliquiritigenin nanocrystals

• Main Authors: Yanni Ma (Author), Xiaoying Yang (Author), Guoting Chen (Author), Yuxin Zhang (Author), Hao Zhang (Author), Wenping Zhang (Author)
• Format: Book
• Published: Universidade de São Paulo, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract As one of the most promising formulations for poorly water-soluble drugs, nanocrystals have been attracting increasing attention in recent years. Isoliquiritigenin (ISL) is a flavonoid with a chalcone structure, and possesses many biological activities. However, its clinical application is...