The Severity of CVB3-Induced Myocarditis Can Be Improved by Blocking the Orchestration of NLRP3 and Th17 in Balb/c Mice

• Main Authors: Jifei Chen (Author), Fan Yang (Author), Song Shi (Author), Xuexiang Liu (Author), Fengxian Qin (Author), Xiaomou Wei (Author), Yujie Huang (Author), Wenwu Liang (Author), Lin Miao (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The functional characteristics of NLRP3 in the pathogenesis of coxsackievirus B3- (CVB3-) induced viral myocarditis (VMC) have not been fully elucidated, and the targeted therapeutic effect of NLRP3 or its related pathway in VMC has not been reported. Method. In this work, the change pat...