Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish

• Main Authors: Suma Choorapoikayil (Author), Bart Weijts (Author), Rianne Kers (Author), Alain de Bruin (Author), Jeroen den Hertog (Author)
• Format: Book
• Published: The Company of Biologists, 2013-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Angiogenesis, the emergence of vessels from an existing vascular network, is pathologically associated with tumor progression and is of great interest for therapeutic intervention. PTEN is a frequently mutated tumor suppressor and has been linked to the progression of many types of tumors, i...