Research and application of single-cell sequencing in tumor heterogeneity and drug resistance of circulating tumor cells
Abstract Malignant tumor is a largely harmful disease worldwide. The cure rate of malignant tumors increases with the continuous discovery of anti-tumor drugs and the optimisation of chemotherapy options. However, drug resistance of tumor cells remains a massive obstacle in the treatment of anti-tum...
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| Main Authors: | , , , , , |
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| Format: | Book |
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BMC,
2020-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Abstract Malignant tumor is a largely harmful disease worldwide. The cure rate of malignant tumors increases with the continuous discovery of anti-tumor drugs and the optimisation of chemotherapy options. However, drug resistance of tumor cells remains a massive obstacle in the treatment of anti-tumor drugs. The heterogeneity of malignant tumors makes studying it further difficult for us. In recent years, using single-cell sequencing technology to study and analyse circulating tumor cells can avoid the interference of tumor heterogeneity and provide a new perspective for us to understand tumor drug resistance. |
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| Item Description: | 10.1186/s40364-020-00240-1 2050-7771 |