Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis - A Report of 2 Cases

Introduction: Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses,...

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Main Authors: Fatemeh Mohaghegh (Author), Zohre Khodashenas (Author), Mina Saber (Author), Haniyeh Sohrabi (Author)
Format: Book
Published: Karger Publishers, 2024-10-01T00:00:00Z.
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100 1 0 |a Fatemeh Mohaghegh  |e author 
700 1 0 |a Zohre Khodashenas  |e author 
700 1 0 |a Mina Saber  |e author 
700 1 0 |a Haniyeh Sohrabi  |e author 
245 0 0 |a Syringotropic Lichen Planus: An Unusual Presentation of a Common Dermatosis - A Report of 2 Cases 
260 |b Karger Publishers,   |c 2024-10-01T00:00:00Z. 
500 |a 1662-6567 
500 |a 10.1159/000541695 
520 |a Introduction: Lichen planus (LP) is a chronic inflammatory dermatosis that causes plaques and itchy papules on the skin, as well as erosion and ulcers in the mucous membranes. LP is characterized by a dense dermal T-cell infiltration. Perieccrine inflammation can be seen in a variety of dermatoses, but genuine lymphocyte permeation of the secretory coil or lymphocytic syringotropism is a rare sign that is typically seen in mycosis fungoides. Case Presentation: In this study, we present 2 uncommon instances of lymphocytic syringotropism in LP. Histopathological examination revealed dense T-cell infiltration and lymphocytic involvement of eccrine glands, confirming syringotropism. Conclusion: Lymphocytic syringotropism is an uncommon finding in LP. Its presence broadens the histopathological spectrum of LP and highlights the need to differentiate it from lymphoproliferative disorders like mycosis fungoides. 
546 |a EN 
690 |a lichen planus 
690 |a mycosis fungoides 
690 |a syringotropic lichen planus 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Case Reports in Dermatology, Vol 16, Iss 1, Pp 226-233 (2024) 
787 0 |n https://beta.karger.com/Article/FullText/541695 
787 0 |n https://doaj.org/toc/1662-6567 
856 4 1 |u https://doaj.org/article/8b0945146b2b4b5eb0c7423f2529c2e8  |z Connect to this object online.