In Silico Prediction of <i>Plasmodium falciparum</i> Cytoadherence Inhibitors That Disrupt Interaction between gC1qR-DBLβ12 Complex

• Main Authors: Abdul Hafiz (Author), Rowaida Bakri (Author), Mohammad Alsaad (Author), Obadah M. Fetni (Author), Lojain I. Alsubaihi (Author), Hina Shamshad (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Malaria causes about half a million deaths per year, mainly in children below 5 years of age. Cytoadherence of <i>Plasmodium falciparum</i> infected erythrocytes in brain and placenta has been linked to severe malaria and malarial related deaths. Cytoadherence is mediated by binding of h...