Efficacy of beta-blockers in the treatment of sepsis
This meta-analysis is to systematically evaluate the efficacy and safety of beta-blockers in the treatment of sepsis. A total of 17 articles that met the inclusion criteria were included, and 10,385 cases were obtained. The meta-analysis results showed that patients with sepsis with beta-blocker usa...
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| Format: | Book |
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Bangladesh Pharmacological Society,
2021-01-01T00:00:00Z.
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| 001 | doaj_8b115268c9c64e77b195e00b6a1c3f3a | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Peng Jin |e author |
| 700 | 1 | 0 | |a Tao Zhao |e author |
| 700 | 1 | 0 | |a Yueyue Wei |e author |
| 700 | 1 | 0 | |a Fang Zhao |e author |
| 245 | 0 | 0 | |a Efficacy of beta-blockers in the treatment of sepsis |
| 260 | |b Bangladesh Pharmacological Society, |c 2021-01-01T00:00:00Z. | ||
| 500 | |a 10.3329/bjp.v16i1.46001 | ||
| 500 | |a 1991-0088 | ||
| 520 | |a This meta-analysis is to systematically evaluate the efficacy and safety of beta-blockers in the treatment of sepsis. A total of 17 articles that met the inclusion criteria were included, and 10,385 cases were obtained. The meta-analysis results showed that patients with sepsis with beta-blocker usage had a significantly lower 28-day mortality. The heart rate decreased over time in patients with sepsis using beta-blocker. Moreover, central venous blood oxygen saturation increased after 24, 48, 72 hours of treatment; lactic acid and cardiac troponin I decreased after 48, 72 hours of treatment; and tumor necrosis factor-α, interleukin-1β levels decreased significantly after 12, 24, 48, 72 hours of treatment (p<0.05). In conclusion, beta-blockers reduce 28-day mortality and heart rate. | ||
| 546 | |a EN | ||
| 690 | |a Beta-blocker | ||
| 690 | |a Meta-analysis | ||
| 690 | |a Sepsis | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Bangladesh Journal of Pharmacology, Vol 16, Iss 1 (2021) | |
| 787 | 0 | |n https://www.banglajol.info/index.php/BJP/article/view/46001 | |
| 787 | 0 | |n https://doaj.org/toc/1991-0088 | |
| 856 | 4 | 1 | |u https://doaj.org/article/8b115268c9c64e77b195e00b6a1c3f3a |z Connect to this object online. |