Lipid Nanoparticles for the Posterior Eye Segment

This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most relevant diseases affecting the posterior seg...

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Bibliographic Details
Main Authors: Lorena Bonilla (Author), Marta Espina (Author), Patricia Severino (Author), Amanda Cano (Author), Miren Ettcheto (Author), Antoni Camins (Author), Maria Luisa García (Author), Eliana B. Souto (Author), Elena Sánchez-López (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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Summary:This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most relevant diseases affecting the posterior segment will be summarized. Moreover, preparation methods and different types and subtypes of lipid nanoparticles will also be reviewed. Lipid nanoparticles used as carriers to deliver drugs to the posterior eye segment as well as their administration routes, pharmaceutical forms and ocular distribution will be discussed emphasizing the different targeting strategies most recently employed for ocular drug delivery.
Item Description:10.3390/pharmaceutics14010090
1999-4923