Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity

Abstract Background The activity of cerebrospinal fluid (CSF) β-site APP cleaving enzyme (BACE) is a potential diagnostic biomarker for Alzheimer disease (AD). Methods A total of 340 non-Hispanic Caucasian participants from the Alzheimer's Disease Neuroimaging Initiative cohort (ADNI) database...

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Main Authors: Hao Hu (Author), Haiyan Li (Author), Jieqiong Li (Author), Jintai Yu (Author), Lan Tan (Author), Alzheimer's Disease Neuroimaging Initiative (Author)
Format: Book
Published: BMC, 2018-05-01T00:00:00Z.
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