Model‐informed approach to support pediatric dosing for the pan‐PI3K inhibitor copanlisib in children and adolescents with relapsed/refractory solid tumors
Abstract Copanlisib is an intravenously administered phosphatidylinositol 3‐kinase (PI3K) inhibitor which was investigated in pediatric patients with relapsed/refractory solid tumors. A model‐informed approach was undertaken to support and confirm an empirically selected starting dose of 28 mg/m2 fo...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Wiley,
2023-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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