Novel [18F]-labeled thiol for the labeling of Dha- or maleimide-containing biomolecules
Abstract Background Prosthetic approach for the radiolabeling of biologics with fluorine-18 is a robust strategy and has been employed for many years. It requires fast, biocompatible and selective reactions suited to these fragile molecules. Michael addition of a nucleophilic thiol moiety on α,β-uns...
Saved in:
Main Authors: | Mylène Richard (Author), Françoise Hinnen (Author), Bertrand Kuhnast (Author) |
---|---|
Format: | Book |
Published: |
SpringerOpen,
2022-04-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Solid-state ¹?F-NMR studies on fluorine-labeled model compounds and biomolecules
by: Dürr, Ulrich Heiner Nikolaus
Published: (2006) -
Automated radiosynthesis of two 18F-labeled tracers containing 3-fluoro-2-hydroxypropyl moiety, [18F]FMISO and [18F]PM-PBB3, via [18F]epifluorohydrin
by: Takayuki Ohkubo, et al.
Published: (2021) -
18F-labeled tracers targeting fibroblast activation protein
by: Thomas Lindner, et al.
Published: (2021) -
A head-to-head comparison of conjugation methods for VHHs: Random maleimide-thiol coupling versus controlled click chemistry
by: Marc V.A. van Moorsel, et al.
Published: (2019) -
Radiosynthesis and evaluation of an 18F-labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma
by: Lukas O. Dialer, et al.
Published: (2018)