LINC00665 Induces Acquired Resistance to Gefitinib through Recruiting EZH2 and Activating PI3K/AKT Pathway in NSCLC

Gefitinib, a tyrosine kinase inhibitor of epidermal growth factor receptor, has been used as the first choice of treatment for advanced non-small-cell lung cancer. However, during the course of treatment, cancer cells often develop resistance to gefitinib without fully understood mechanisms. In this...

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Main Authors: Xinyin Liu (Author), Xiyi Lu (Author), Fuxi Zhen (Author), Shidai Jin (Author), Tongfu Yu (Author), Quan Zhu (Author), Wei Wang (Author), Kun Xu (Author), Jiaqi Yao (Author), Renhua Guo (Author)
Format: Book
Published: Elsevier, 2019-06-01T00:00:00Z.
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