Review on COVID-19: Rise of SARS-CoV-2 Pandemic Outbreak

• Main Authors: Vidhan Chand Bala (Author), Punet Kumar (Author)
• Format: Book
• Published: Institute for Researches and Community Services Universitas Muhammadiyah Palangkaraya, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2621-4814; 10.33084/bjop.v3iSpecial-1.1412
• Keywords: covid-19; coronavirus; 2019-ncov; sars-cov; mers-cov; Pharmacy and materia medica; RS1-441
• Source: Borneo Journal of Pharmacy, Vol 3, Iss Special-1, Pp 103-120 (2020)

Initially recognized of COVID-19 within the world in 2019, the World Health Organization situational report from May 22nd, 2020, globally, there is a complete of 5,204,508 confirmed cases, with 212 countries being affected by the novel coronavirus. 2019 novel coronavirus (SARS-CoV-2) is that the seventh member of the family of coronaviruses is enveloped viruses with a positive sense, single-stranded RNA genome. The SARS-CoV-2 may be a β-CoV of group 2B there is 70% comparability in genetic sequence to SARS-CoV. The source of the new coronavirus infection has been resolved as bats. With whole-genome sequences of SARS-CoV-2 is 96% comparatively at the whole-genome level to a bat coronavirus. Mechanisms of transmission are concluded to incorporate contact, droplet, and possibly airborne under certain circumstances supported ancient experiences associated with SARS-CoV outbreaks. Although antiretroviral therapy is being widely used everywhere the globe for such patents, effects at finding a SARS-CoV vaccine haven't succeeded so far.