Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation
Abstract Background Germline mutations in the RUNX1 transcription factor give rise to a rare autosomal dominant genetic condition classified under the entity: Familial Platelet Disorders with predisposition to Acute Myeloid Leukaemia (FPD/AML). While several studies have identified a myriad of germl...
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Main Authors: | Isaac KS Ng (Author), Joanne Lee (Author), Christopher Ng (Author), Bustamin Kosmo (Author), Lily Chiu (Author), Elaine Seah (Author), Michelle Meng Huang Mok (Author), Karen Tan (Author), Motomi Osato (Author), Wee-Joo Chng (Author), Benedict Yan (Author), Lip Kun Tan (Author) |
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Format: | Book |
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BMC,
2018-05-01T00:00:00Z.
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