Heparanase contributes to psoriatic lesions through crosstalk with IL-17 pathway

• Main Authors: Chengyao Zhu (Author), Yunqin Ren (Author), Hongliang Yao (Author), Bo Feng (Author), Lunfei Liu (Author), Min Zheng (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Psoriasis is a chronic inflammatory disease that is considered by a network of immunocytes and cytokines. Among all, Th17 cells-derived IL-17 is a critical driving factor in the pathogenesis of psoriasis. Recently, disruption of the extracellular matrix was found to be related to psoriasis progressi...