Inflammation of Actinic Keratoses Induced by Combination of Carboplatin and Paclitaxel: Two Case Reports

The observations of a beneficial effect of 5-fluorouracil-induced actinic keratoses (AK) inflammation led to the development of topical fluorouracil, a product registered for the management of AK. A conscientious surveillance of AK inflammation during chemotherapy may conceivably lead to the develop...

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Glavni autori: Špela Šuler Baglama (Autor), Anja Trajber Horvat (Autor), Irena Peteln (Autor), Gregor Borut Ernst Jemec (Autor)
Format: Knjiga
Izdano: Karger Publishers, 2022-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Špela Šuler Baglama  |e author 
700 1 0 |a Anja Trajber Horvat  |e author 
700 1 0 |a Irena Peteln  |e author 
700 1 0 |a Gregor Borut Ernst Jemec  |e author 
245 0 0 |a Inflammation of Actinic Keratoses Induced by Combination of Carboplatin and Paclitaxel: Two Case Reports 
260 |b Karger Publishers,   |c 2022-12-01T00:00:00Z. 
500 |a 1662-6567 
500 |a 10.1159/000528128 
520 |a The observations of a beneficial effect of 5-fluorouracil-induced actinic keratoses (AK) inflammation led to the development of topical fluorouracil, a product registered for the management of AK. A conscientious surveillance of AK inflammation during chemotherapy may conceivably lead to the development of further drugs for treatment of AK. A number of other chemotherapeutics have thus been linked to similar reactions without ensuing development. Here, we describe two further cases linking chemotherapy with carboplatin and paclitaxel to possible anti-AK effects, identifying them as potential treatments. Whether multidrug chemotherapy leads to stronger AK inflammation or cure AK more successfully is currently unknown. 
546 |a EN 
690 |a actinic keratoses 
690 |a inflammation 
690 |a chemotherapy 
690 |a carboplatin 
690 |a paclitaxel 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Case Reports in Dermatology, Vol 14, Iss 3, Pp 362-367 (2022) 
787 0 |n https://www.karger.com/Article/FullText/528128 
787 0 |n https://doaj.org/toc/1662-6567 
856 4 1 |u https://doaj.org/article/8c32a32404ee4fc3a1704d90bd0bc38f  |z Connect to this object online.