Inflammation of Actinic Keratoses Induced by Combination of Carboplatin and Paclitaxel: Two Case Reports
The observations of a beneficial effect of 5-fluorouracil-induced actinic keratoses (AK) inflammation led to the development of topical fluorouracil, a product registered for the management of AK. A conscientious surveillance of AK inflammation during chemotherapy may conceivably lead to the develop...
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Karger Publishers,
2022-12-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_8c32a32404ee4fc3a1704d90bd0bc38f | ||
042 | |a dc | ||
100 | 1 | 0 | |a Špela Šuler Baglama |e author |
700 | 1 | 0 | |a Anja Trajber Horvat |e author |
700 | 1 | 0 | |a Irena Peteln |e author |
700 | 1 | 0 | |a Gregor Borut Ernst Jemec |e author |
245 | 0 | 0 | |a Inflammation of Actinic Keratoses Induced by Combination of Carboplatin and Paclitaxel: Two Case Reports |
260 | |b Karger Publishers, |c 2022-12-01T00:00:00Z. | ||
500 | |a 1662-6567 | ||
500 | |a 10.1159/000528128 | ||
520 | |a The observations of a beneficial effect of 5-fluorouracil-induced actinic keratoses (AK) inflammation led to the development of topical fluorouracil, a product registered for the management of AK. A conscientious surveillance of AK inflammation during chemotherapy may conceivably lead to the development of further drugs for treatment of AK. A number of other chemotherapeutics have thus been linked to similar reactions without ensuing development. Here, we describe two further cases linking chemotherapy with carboplatin and paclitaxel to possible anti-AK effects, identifying them as potential treatments. Whether multidrug chemotherapy leads to stronger AK inflammation or cure AK more successfully is currently unknown. | ||
546 | |a EN | ||
690 | |a actinic keratoses | ||
690 | |a inflammation | ||
690 | |a chemotherapy | ||
690 | |a carboplatin | ||
690 | |a paclitaxel | ||
690 | |a Dermatology | ||
690 | |a RL1-803 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Case Reports in Dermatology, Vol 14, Iss 3, Pp 362-367 (2022) | |
787 | 0 | |n https://www.karger.com/Article/FullText/528128 | |
787 | 0 | |n https://doaj.org/toc/1662-6567 | |
856 | 4 | 1 | |u https://doaj.org/article/8c32a32404ee4fc3a1704d90bd0bc38f |z Connect to this object online. |