Inflammatory Breast Cancer and Warm Antibody Autoimmune Hemolytic Anemia: A Rare Paraneoplastic Syndrome

Autoimmune hemolytic anemia (AIHA) is a disease process that involves the destruction of red blood cells mediated by the humoral immune system. It can be characterized as a cold agglutinin syndrome, paroxysmal cold hemoglobinuria, and warm, mixed type, and drug-induced AIHA. Although a well-establis...

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Main Authors: Nene Ugoeke MD, MPH (Author), Chidinma Onweni MD (Author), Jennifer Treece MD, MBA (Author), Vandana Pai MD (Author), Sowminya Arikapudi MD (Author), Evan Kulbacki MD (Author), Kailash Bajaj MD, MPH (Author)
Format: Book
Published: SAGE Publishing, 2017-11-01T00:00:00Z.
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100 1 0 |a Nene Ugoeke MD, MPH  |e author 
700 1 0 |a Chidinma Onweni MD  |e author 
700 1 0 |a Jennifer Treece MD, MBA  |e author 
700 1 0 |a Vandana Pai MD  |e author 
700 1 0 |a Sowminya Arikapudi MD  |e author 
700 1 0 |a Evan Kulbacki MD  |e author 
700 1 0 |a Kailash Bajaj MD, MPH  |e author 
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260 |b SAGE Publishing,   |c 2017-11-01T00:00:00Z. 
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520 |a Autoimmune hemolytic anemia (AIHA) is a disease process that involves the destruction of red blood cells mediated by the humoral immune system. It can be characterized as a cold agglutinin syndrome, paroxysmal cold hemoglobinuria, and warm, mixed type, and drug-induced AIHA. Although a well-established relationship exists between the presence of AIHA and lymphoproliferative malignancy, AIHA rarely presents in association with solid malignancies. An analysis of the limited number of published cases of AIHA in association with solid malignancies performed showed that AIHA may present before the diagnosis of a solid malignancy, concurrently with the presence of a solid malignancy, or even on resolution of a solid malignancy. Few cases of solid cancers associated with AIHA have been reported. AIHA rarely presents as a paraneoplastic syndrome indicating existence of a solid cancer. We report a case of inflammatory breast cancer with AIHA. 
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690 |a Medicine (General) 
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690 |a Pathology 
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786 0 |n Journal of Investigative Medicine High Impact Case Reports, Vol 5 (2017) 
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787 0 |n https://doaj.org/toc/2324-7096 
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