Pharmacological inhibition of the PI3K/PTEN/Akt and mTOR signalling pathways limits follicle activation induced by ovarian cryopreservation and in vitro culture
Abstract Background Cryopreservation and transplantation of ovarian tissue (OTCTP) represent a promising fertility preservation technique for prepubertal patients or for patients requiring urgent oncological management. However, a major obstacle of this technique is follicle loss due to, among other...
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Main Authors: | Carmen Terren (Author), Michelle Nisolle (Author), Carine Munaut (Author) |
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Format: | Book |
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BMC,
2021-07-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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