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Simultaneous determination of ezetimibe and simvastatin in rat plasma by stable-isotope dilution LC-ESIâMS/MS and its application to a pharmacokinetic study

A simple, sensitive and specific liquid chromatographyâtandem mass spectrometry method was developed for simultaneous quantification of ezetimibe and simvastatin in rat plasma. The deuterium isotopes: ezetimibe d4 and simvastatin d6 were used as internal standards for ezetimibe and simvastatin, resp...

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Bibliographic Details
Main Authors:	Sireesha R. Karanam (Author), Prakash Katakam (Author), Babu R. Chandu (Author), Nagiat T. Hwisa (Author), Shanta K. Adiki (Author)
Format:	Book
Published:	Elsevier, 2014-08-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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