Identification of Natural Products as SENP2 Inhibitors for Targeted Therapy in Heart Failure
Aims: Sentrin-specific protease -2 (SENP2) is involved in deSUMOylation. Increased deSUMOylation in murine hearts by SENP2 upregulation resulted in cardiac dysfunction and congenital heart defects. Natural compounds via regulating cell proliferation and survival, induce cell cycle cessation, cell de...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2022-04-01T00:00:00Z.
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