Cytokine profiling in plasma distinguishes the histological inflammatory subtype of head and neck squamous cell carcinoma and a novel regulatory role of osteopontin

• Egile Nagusiak: Ioana Ghita (Egilea), Evangelia Piperi (Egilea), Sergei P. Atamas (Egilea), Soren M. Bentzen (Egilea), Robert A. Ord (Egilea), Donita Dyalram (Egilea), Joshua E. Lubek (Egilea), Rania H. Younis (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Head and neck squamous cell carcinoma (HNSCC) can be classified according to the histological inflammatory subtype (HIS) into inflamed (HIS-INF) or immune excluded (HIS-IE). HIS-IE was previously associated with higher levels of soluble Semaphorin 4D (HsS4D) in plasma, and higher transcriptional lev...