Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents.
New treatments are needed for neglected tropical diseases (NTDs) such as Human African trypanosomiasis (HAT), Chagas disease, and schistosomiasis. Through a whole organism high-throughput screening campaign, we previously identified 797 human kinase inhibitors that grouped into 59 structural cluster...
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Main Authors: | Dana M Klug (Author), Rosario Diaz-Gonzalez (Author), Guiomar Pérez-Moreno (Author), Gloria Ceballos-Pérez (Author), Raquel García-Hernández (Author), Veronica Gomez-Pérez (Author), Luis Miguel Ruiz-Pérez (Author), Domingo I Rojas-Barros (Author), Francisco Gamarro (Author), Dolores González-Pacanowska (Author), María S Martínez-Martínez (Author), Pilar Manzano (Author), Lori Ferrins (Author), Conor R Caffrey (Author), Miguel Navarro (Author), Michael P Pollastri (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2019-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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