The Relationship between Cancer and Paraoxonase 1

Extensive research has been carried out to understand and elucidate the mechanisms of paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular diseases, neurological diseases, and inflammatory diseases. This review focuses on the relationship between PON1 and cancer. The...

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Main Authors: Irma Martha Medina-Díaz (Author), Néstor Ponce-Ruíz (Author), Aurora Elizabeth Rojas-García (Author), José Francisco Zambrano-Zargoza (Author), Yael Y. Bernal-Hernández (Author), Cyndia Azucena González-Arias (Author), Briscia S. Barrón-Vivanco (Author), José Francisco Herrera-Moreno (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Irma Martha Medina-Díaz  |e author 
700 1 0 |a Néstor Ponce-Ruíz  |e author 
700 1 0 |a Aurora Elizabeth Rojas-García  |e author 
700 1 0 |a José Francisco Zambrano-Zargoza  |e author 
700 1 0 |a Yael Y. Bernal-Hernández  |e author 
700 1 0 |a Cyndia Azucena González-Arias  |e author 
700 1 0 |a Briscia S. Barrón-Vivanco  |e author 
700 1 0 |a José Francisco Herrera-Moreno  |e author 
245 0 0 |a The Relationship between Cancer and Paraoxonase 1 
260 |b MDPI AG,   |c 2022-03-01T00:00:00Z. 
500 |a 10.3390/antiox11040697 
500 |a 2076-3921 
520 |a Extensive research has been carried out to understand and elucidate the mechanisms of paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular diseases, neurological diseases, and inflammatory diseases. This review focuses on the relationship between PON1 and cancer. The data suggest that PON1, oxidative stress, chronic inflammation, and cancer are closely linked. Certainly, the gene expression of PON1 will remain challenging to study. Therefore, targeting PON1, redox-sensitive pathways, and transcription factors promise prevention and therapy in the development of several diseases, including cancer. 
546 |a EN 
690 |a cancer 
690 |a PON1 
690 |a inflammation 
690 |a oxidative stress 
690 |a PON1 activity 
690 |a transcriptional factors 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Antioxidants, Vol 11, Iss 4, p 697 (2022) 
787 0 |n https://www.mdpi.com/2076-3921/11/4/697 
787 0 |n https://doaj.org/toc/2076-3921 
856 4 1 |u https://doaj.org/article/8cc8c5b3d7da41d19eac97d356670bf1  |z Connect to this object online.