Platelet Protease Activated Receptor 1 Is Involved in the Hemostatic Effect of 20(S)-Protopanaxadiol by Regulating Calcium Signaling

• Main Authors: He Zhang (Author), Daian Pan (Author), Xingquan Wu (Author), Wenjie Su (Author), Xiaolei Tang (Author), Daqing Zhao (Author), Liwei Sun (Author), Bailin Song (Author), Xueyuan Bai (Author), Xiangyan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Panax notoginseng (Burk.) F.H. Chen has long been used to stop bleeding for hundreds of years in China. At present, only dencichine, notoginsenoside Ft1, and 20(S)-protopanaxadiol (PPD) showed hemostatic effect. However, the molecular mechanism of PPD on the platelet aggragetion needs to be further...