The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts

In our previous research, we demonstrated that honey and its biomimetic natural deep eutectic solvent (NaDES) modulate the antioxidant activity (AOA) of the raspberry extract (RE). In this study, we evaluated the AOA behaviour of the mixture honey/NaDES-honeysuckle (<i>Lonicera caprifolium,<...

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Main Authors: Luminița Dimitriu (Author), Diana Constantinescu-Aruxandei (Author), Daniel Preda (Author), Ionuț Moraru (Author), Narcisa Elena Băbeanu (Author), Florin Oancea (Author)
Format: Book
Published: MDPI AG, 2023-08-01T00:00:00Z.
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100 1 0 |a Luminița Dimitriu  |e author 
700 1 0 |a Diana Constantinescu-Aruxandei  |e author 
700 1 0 |a Daniel Preda  |e author 
700 1 0 |a Ionuț Moraru  |e author 
700 1 0 |a Narcisa Elena Băbeanu  |e author 
700 1 0 |a Florin Oancea  |e author 
245 0 0 |a The Antioxidant and Prebiotic Activities of Mixtures Honey/Biomimetic NaDES and Polyphenols Show Differences between Honeysuckle and Raspberry Extracts 
260 |b MDPI AG,   |c 2023-08-01T00:00:00Z. 
500 |a 10.3390/antiox12091678 
500 |a 2076-3921 
520 |a In our previous research, we demonstrated that honey and its biomimetic natural deep eutectic solvent (NaDES) modulate the antioxidant activity (AOA) of the raspberry extract (RE). In this study, we evaluated the AOA behaviour of the mixture honey/NaDES-honeysuckle (<i>Lonicera caprifolium,</i> LFL) extract and compared it with the mixture honey/NaDES-RE. These two extracts have similar major flavonoids and hydroxycinnamic acid compounds but differ in their total content and the presence of anthocyanins in RE. Therefore, it was of interest to see if the modulation of the LFL polyphenols by honey/NaDES was similar to that of RE. We also evaluated the prebiotic activity of these mixtures and individual components on <i>Limosilactobacillus reuteri</i> DSM 20016. Although honey/NaDES modulated the AOA of both extracts, from synergism to antagonism, the modulation was different between the two extracts for some AOA activities. Honey/NaDES mixtures enriched with LFL and RE did not show significant differences in bacterial growth stimulation. However, at a concentration of 45 mg/mL, the honey -LFL mixture exhibited a higher effect compared to the honey-RE mixture. The antioxidant and prebiotic properties of mixtures between honey and polyphenol-rich extracts are determined by multiple interactions in complex chemical systems. 
546 |a EN 
690 |a honey 
690 |a biomimetic natural deep eutectic solvents 
690 |a <i>Lonicera caprifolium</i> 
690 |a lactic acid production 
690 |a <i>Limosilactobacillus reuteri</i> 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Antioxidants, Vol 12, Iss 9, p 1678 (2023) 
787 0 |n https://www.mdpi.com/2076-3921/12/9/1678 
787 0 |n https://doaj.org/toc/2076-3921 
856 4 1 |u https://doaj.org/article/8cda6d9a62af4875a1d71ed061d8da7e  |z Connect to this object online.