3D-QSAR, Molecular Docking, and MD Simulations of Anthraquinone Derivatives as PGAM1 Inhibitors

• প্রধান লেখক: Yuwei Wang (লেখক), Yifan Guo (লেখক), Shaojia Qiang (লেখক), Ruyi Jin (লেখক), Zhi Li (লেখক), Yuping Tang (লেখক), Elaine Lai Han Leung (লেখক), Hui Guo (লেখক), Xiaojun Yao (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

PGAM1 is overexpressed in a wide range of cancers, thereby promoting cancer cell proliferation and tumor growth, so it is gradually becoming an attractive target. Recently, a series of inhibitors with various structures targeting PGAM1 have been reported, particularly anthraquinone derivatives. In p...