Joint and interactive associations of body mass index and genetic factors with cardiovascular disease: a prospective study in UK Biobank

• Main Authors: Ruyu Huang (Author), Xinxin Kong (Author), Rui Geng (Author), Jingwei Wu (Author), Tao Chen (Author), Jiong Li (Author), Chunjian Li (Author), Yaqian Wu (Author), Dongfang You (Author), Yang Zhao (Author), Zihang Zhong (Author), Senmiao Ni (Author), Jianling Bai (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Both body mass index (BMI) and genetic factors independently contribute to cardiovascular disease (CVD). However, it is unclear whether genetic risk modifies the association between BMI and the risk of incident CVD. This study aimed to investigate whether BMI categories and genet...