Negative correlation between maorophage proooagulant and migraion ability in the course of inflammation

The importance of macrophage procoagulant activity (PCA) to cell migration is presumed. In this study we assayed the relationship between the two functions in guinea-pig peritoneal resident macrophages and cells elicited by a sterile inflammation induction, which lasted up to 6 days. The findings po...

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Bibliographic Details
Main Authors: I. Vilic (Author), L. M. Prokic (Author)
Format: Book
Published: Hindawi Limited, 1996-01-01T00:00:00Z.
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100 1 0 |a I. Vilic  |e author 
700 1 0 |a L. M. Prokic  |e author 
245 0 0 |a Negative correlation between maorophage proooagulant and migraion ability in the course of inflammation 
260 |b Hindawi Limited,   |c 1996-01-01T00:00:00Z. 
500 |a 0962-9351 
500 |a 1466-1861 
500 |a 10.1155/S0962935196000397 
520 |a The importance of macrophage procoagulant activity (PCA) to cell migration is presumed. In this study we assayed the relationship between the two functions in guinea-pig peritoneal resident macrophages and cells elicited by a sterile inflammation induction, which lasted up to 6 days. The findings pointed to an in vivo induction of PCA in macrophages, which declined with time during inflammation. A clear negative correlation between PCA and random migration ability was demonstrated. Our results suggest that the local induction of coagulation by macrophages may immobilize the cells at the site of inflammation. 
546 |a EN 
690 |a Pathology 
690 |a RB1-214 
655 7 |a article  |2 local 
786 0 |n Mediators of Inflammation, Vol 5, Iss 4, Pp 271-275 (1996) 
787 0 |n http://dx.doi.org/10.1155/S0962935196000397 
787 0 |n https://doaj.org/toc/0962-9351 
787 0 |n https://doaj.org/toc/1466-1861 
856 4 1 |u https://doaj.org/article/8d2b28830c42452a98fcbc89ea4dcbb1  |z Connect to this object online.