Anticonvulsant Action of GluN2A-Preferring Antagonist PEAQX in Developing Rats
The GluN2A subunit of N-methyl-D-aspartate (NMDA) receptors becomes dominant during postnatal development, overgrowing the originally dominant GluN2B subunit. The aim of our study was to show changes of anticonvulsant action of the GluN2A subunit-preferring antagonist during postnatal development of...
Saved in:
Main Authors: | Pavel Mares (Author), Grygoriy Tsenov (Author), Hana Kubova (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2021-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The GluN2B-Selective Antagonist Ro 25-6981 Is Effective against PTZ-Induced Seizures and Safe for Further Development in Infantile Rats
by: Pavel Mareš, et al.
Published: (2021) -
GluN2A and GluN2B N-Methyl-D-Aspartate Receptor (NMDARs) Subunits: Their Roles and Therapeutic Antagonists in Neurological Diseases
by: Amany Digal Ladagu, et al.
Published: (2023) -
The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains
by: Eva Kudova, et al.
Published: (2021) -
Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors
by: Yue Zeng, et al.
Published: (2022) -
GluN2B but Not GluN2A for Basal Dendritic Growth of Cortical Pyramidal Neurons
by: Steffen Gonda, et al.
Published: (2020)