Biological Tools to Study the Effects of Environmental Contaminants at the Feto-Maternal Interface

The identification of reproductive toxicants is a major scientific challenge for human health. Prenatal life is the most vulnerable and important time span of human development. For obvious ethical reasons, in vivo models cannot be used in human pregnancy, and animal models do not perfectly reflect...

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Bibliographic Details
Main Authors: Chiara Mannelli (Author), Francesca Ietta (Author), Anna Maria Avanzati (Author), Dariusz Skarzynski (Author), Luana Paulesu (Author)
Format: Book
Published: SAGE Publishing, 2015-11-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Chiara Mannelli  |e author 
700 1 0 |a Francesca Ietta  |e author 
700 1 0 |a Anna Maria Avanzati  |e author 
700 1 0 |a Dariusz Skarzynski  |e author 
700 1 0 |a Luana Paulesu  |e author 
245 0 0 |a Biological Tools to Study the Effects of Environmental Contaminants at the Feto-Maternal Interface 
260 |b SAGE Publishing,   |c 2015-11-01T00:00:00Z. 
500 |a 1559-3258 
500 |a 10.1177/1559325815611902 
520 |a The identification of reproductive toxicants is a major scientific challenge for human health. Prenatal life is the most vulnerable and important time span of human development. For obvious ethical reasons, in vivo models cannot be used in human pregnancy, and animal models do not perfectly reflect human physiology. This review describes the in vitro test models representative of the human feto-maternal interface and the effects of environmental chemicals with estrogen-like activity, mainly bisphenol A and para-nonylphenol, with a particular emphasis on the effects at low, nontoxic doses similar to concentrations commonly detected in the population. 
546 |a EN 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Dose-Response, Vol 13 (2015) 
787 0 |n https://doi.org/10.1177/1559325815611902 
787 0 |n https://doaj.org/toc/1559-3258 
856 4 1 |u https://doaj.org/article/8d347844c2014a128d25f3b6b6fe029a  |z Connect to this object online.