Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison
In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549, HepG2 and C6. Their structures were elucidated by IR, 1H-NMR, 13C-NMR, 2 D-NMR and HRMS spectroscopic methods. Among al...
Saved in:
Main Authors: | Ulviye Acar Çevik (Author), Begüm Nurpelin Sağlık (Author), Derya Osmaniye (Author), Serkan Levent (Author), Betül Kaya Çavuşoğlu (Author), Abdullah Burak Karaduman (Author), Özlem Atlı Eklioğlu (Author), Yusuf Özkay (Author), Zafer Asım Kaplancıklı (Author) |
---|---|
Format: | Book |
Published: |
Taylor & Francis Group,
2020-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Synthesis, in vitro enzyme activity and molecular docking studies of new benzylamine-sulfonamide derivatives as selective MAO-B inhibitors
by: Begüm Nurpelin Sağlık, et al.
Published: (2020) -
Design, synthesis, and evaluation of novel 2-phenylpropionic acid derivatives as dual COX inhibitory-antibacterial agents
by: Hülya Karaca Gençer, et al.
Published: (2017) -
Novel 1-(2-pyrimidin-2-yl)piperazine derivatives as selective monoamine oxidase (MAO)-A inhibitors
by: Betül Kaya, et al.
Published: (2017) -
In silico and antithrombotic studies of 1,3,4-oxadiazoles derived from benzimidazole
by: B. Vishwanathan, et al.
Published: (2015) -
In-silico ADME prediction and molecular docking study of novel benzimidazole-1,3,4-oxadiazole derivatives as CYP51 inhibitors for antimicrobial activity
by: Shivanand Kolageri, et al.
Published: (2022)