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Inhibition of Liquid-Liquid Phase Separation for Breaking the Solubility Barrier of Amorphous Solid Dispersions to Improve Oral Absorption of Naftopidil

Amorphous solid dispersion (ASD) is one of the most promising technologies for improving the oral absorption of poorly soluble compounds. In this study, naftopidil (NFT) ASDs were prepared using vinylpyrrolidone-vinyl acetate copolymer (PVPVA), hydroxypropyl methylcellulose acetate succinate (HPMCAS...

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Bibliographic Details
Main Authors:	Masafumi Fukiage (Author), Kyosuke Suzuki (Author), Maki Matsuda (Author), Yohei Nishida (Author), Michinori Oikawa (Author), Takuya Fujita (Author), Kohsaku Kawakami (Author)
Format:	Book
Published:	MDPI AG, 2022-11-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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