Lumbosacral Soft Tissue Mass in a Newborn: A Clinical Case with a Difficult Diagnosis

• Main Authors: Simone Ceratto (Author), Maria Eleonora Basso (Author), Francesco Savino (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2296-2360; 10.3389/fped.2017.00226
• Keywords: soft-tissue lesions; neoplasms; newborn; lumbosacral region; pediatric oncology; Pediatrics; RJ1-570
• Source: Frontiers in Pediatrics, Vol 5 (2017)

Many types of dorsal neoplasm of early infancy are described in literature ranging from benign to aggressive. Some are more common while others quite unusual. Here, we describe a newborn with a lumbosacral soft tissue mass. Positivity of S-100 and vimentin was compatible with the neural cell line and the high proliferation rate of major activity cells (biopsy Ki67 20%) suggests an aggressive nature. An exclusively surgical approach was chosen and no clinical or radiological signs of recurrence have been observed after 2 years of follow-up. This case is atypical for location, histological pattern, radiological aspect, and clinical behavior. Diagnosis is hard to define and limited to a mesenchymal neoplasia with myxoid tracts. The described aspects raise concerns about clinical and therapeutic approach, classification, and radiological follow-up of sacral tissue masses in newborns.