Specific Inhibition of SRC Kinase Impairs Malignant Glioma Growth In Vitro and In Vivo

• Main Authors: Hanna Stedt (Author), Laura Alasaarela (Author), Haritha Samaranayake (Author), Jere Pikkarainen (Author), Ann-Marie Määttä (Author), Ivana Kholová (Author), Aaron S. Parker (Author), Seppo Ylä-Herttuala (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Malignant glioma is a severe cancer with a poor prognosis. Local occurrence and rare metastases of malignant glioma make it a suitable target for gene therapy. Several studies have demonstrated the importance of Src kinase in different cancers. However, these studies have focused mainly on Src-defic...