Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

• Main Authors: Xin Sun (Author), Yuhan Shu (Author), Guiqin Ye (Author), Caixia Wu (Author), Mengting Xu (Author), Ruilan Gao (Author), Dongsheng Huang (Author), Jianbin Zhang (Author)
• Format: Book
• Published: Elsevier, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parkin, an E3 ubiquitin ligase, plays a role in maintaining mitochondrial homeostasis through targeting damaged mitochondria for mitophagy. Accumulating evidence suggests that the acetylation modification of the key mitophagy machinery influences mitophagy level, but the underlying mechanism is poor...