In Situ Monitoring of Drug Precipitation from Digesting Lipid Formulations Using Low-Frequency Raman Scattering Spectroscopy

• Egile Nagusiak: Malinda Salim (Egilea), Sara J. Fraser-Miller (Egilea), Kārlis Bērziņš (Egilea), Joshua J. Sutton (Egilea), Keith C. Gordon (Egilea), Ben J. Boyd (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Low-frequency Raman spectroscopy (LFRS) is a valuable tool to detect the solid state of amorphous and crystalline drugs in solid dosage forms and the transformation of drugs between different polymorphic forms. It has also been applied to track the solubilisation of solid drugs as suspensions in mil...