Huperzine A provides robust and sustained protection against induced seizures in Scn1a mutant mice
De novo loss-of-function mutations in the voltage-gated sodium channel (VGSC) SCN1A (encoding Nav1.1) are the main cause of Dravet syndrome (DS), a catastrophic early-life encephalopathy associated with prolonged and recurrent early-life febrile seizures (FSs), refractory afebrile epilepsy, cognitiv...
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Main Authors: | Jennifer C. Wong (Author), Stacey B.B. Dutton (Author), Stephen D. Collins (Author), Steven Schachter (Author), Andrew Escayg (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2016-10-01T00:00:00Z.
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