Chalcone-Derived Nrf2 Activator Protects Cognitive Function via Maintaining Neuronal Redox Status
NF-E2-related factor 2 (Nrf2), the key transcription regulator of phase II enzymes, has been considered beneficial for neuronal protection. We previously designed a novel chalcone analog, 1-(2,3,4-trimethoxyphenyl)-2-(3,4,5-trimethoxyphenyl)-acrylketone (Tak), that could specifically activate Nrf2 i...
Saved in:
Main Authors: | Yuting Cui (Author), Yue Xiong (Author), Hua Li (Author), Mengqi Zeng (Author), Yan Wang (Author), Yuan Li (Author), Xuan Zou (Author), Weiqiang Lv (Author), Jing Gao (Author), Ruijun Cao (Author), Lingjie Meng (Author), Jiangang Long (Author), Jiankang Liu (Author), Zhihui Feng (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2021-11-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Hydrogen: A Rising Star in Gas Medicine as a Mitochondria-Targeting Nutrient via Activating Keap1-Nrf2 Antioxidant System
by: Danyu Cheng, et al.
Published: (2023) -
The Flavonoid Hesperidin Methyl Chalcone Targets Cytokines and Oxidative Stress to Reduce Diclofenac-Induced Acute Renal Injury: Contribution of the Nrf2 Redox-Sensitive Pathway
by: Allan J. C. Bussmann, et al.
Published: (2022) -
The Cutaneous Physiological Redox: Essential to Maintain but Difficult to Define
by: Sapir Ron-Doitch, et al.
Published: (2020) -
Comparative Study of Hydroxytyrosol Acetate and Hydroxytyrosol in Activating Phase II Enzymes
by: Xuan Zou, et al.
Published: (2023) -
The effects of trans-chalcone and chalcone 4 hydrate on the growth of Babesia and Theileria.
by: Gaber El-Saber Batiha, et al.
Published: (2019)