Role of DFNB1 mutations in hereditary hearing loss among assortative mating hearing impaired families from South India

• Main Authors: Pavithra Amritkumar (Author), Justin Margret Jeffrey (Author), Jayasankaran Chandru (Author), Paridhy Vanniya S (Author), M. Kalaimathi (Author), Rajagopalan Ramakrishnan (Author), N. P. Karthikeyen (Author), C. R. Srikumari Srisailapathy (Author)
• Format: Book
• Published: BMC, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background DFNB1, the first locus to have been associated with deafness, has two major genes GJB2 & GJB6, whose mutations have played vital role in hearing impairment across many ethnicities in the world. In our present study we have focused on the role of these mutations in assortative...