A novel class of apical sodium--dependent bile salt transporter inhibitors: 1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides
The apical sodium--dependent bile acid transporter (ASBT) is the main transporter to promote re-absorption of bile acids from the intestinal tract into the enterohepatic circulation. Inhibition of ASBT could increase the excretion of bile acids, thus increasing bile acid synthesis and consequently c...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2017-03-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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